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OCs and Brain Structure and Function: Connectivity Given that resting-state functional connectivity (rsFC) is a relatively recent advance in the neuroimaging field, very few studies have explored the effects of OC on rsFC

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Single-cell RNA sequencing and mass cytometry analyses of peripheral blood from smokers have demonstrated expansion of differentiated CD16 + CD8 + T-cell populations, reduced nave T-cell representation, and transcriptional programs consistent with altered cytotoxic function and immune aging (64)

As commonly used, about 8 pregnancies yy per 100 women using COCs over the first year